AI is becoming increasingly pervasive in many aspects of modern life. On a professional level, organizations must gain a deeper understanding of the cultural barriers hindering AI adoption in large businesses and the pivotal role of leadership in addressing these challenges. In this thought-provoking session, our panellists will explore practical strategies for fostering an AI-ready culture, emphasizing the importance of communication, education, and cross-functional collaboration. The panel will focus on the human and ethical aspects of AI, including concerns about job displacement and the necessity for responsible AI practices. Finally, panellists will discuss how to measure the impact of cultural change on AI adoption and strategies for sustaining this change.